Panadrex PURE contains Paracetamol which belongs to a group of medicines called analgesics and antipyretics. The mechanism of action is probably similar to that of aspirin and dependent on the selective inhibition of prostaglandin synthesis.<\/p>\n
Indications:
\n* Mild to moderate pain associated with toothache, headache, earache, backache, sore throat, dysmenorrhea, migraine, neuralgia, rheumatic aches and teething pain.
\n* Fever associated with influenza, bacterial infections, inflammations, colds and childhood infections like chickenpox, measles, mumps and reactions to vaccinations.<\/p>\n
Posology:
\n* Adults and children \u2265 16 years: 1-2 tablets every 4-6 hours (Do not exceed 8 tablets in 24 hours)
\n* Children 10-15 years: 1 tablet every 4-6 hours (Do not exceed 4 tablets in 24 hours)<\/p>\n
Precautions:
\n\u2022 Do not exceed the stated dose.
\n\u2022 Do not take more frequently than every 4 hours.
\n\u2022 Used with caution in patients with severe kidney or liver problems, alcoholic liver disease, and glutathione depleted states
\n\u2022 Paracetamol overdose may cause liver failure.
\n\u2022 Patients should follow the advice of their doctor regarding its use in pregnancy. Available published data does not contraindicate breastfeeding.<\/p>\n
Contraindications:
\n* Hypersensitivity to the active substance or any of the excipients.
\n\u2022 If patient takes other paracetamol-containing medications<\/p>\n
Undesirable effects:
\nSide effects of paracetamol are rare and usually mild, though hematological reactions including thrombocytopenia, leucopenia, pancytopenia, neutropenia, and agranulocytosis have been reported. Skin rash and other hypersensitivity reactions occur occasionally.<\/p>\n
Pharmacokinetic properties:
\n\u2022 Paracetamol is rapidly and almost completely absorbed from the gastrointestinal tract. The concentration in plasma reaches a peak in 30 to 60 minutes and the plasma half-life is 1 \u2013 4 hours after therapeutic doses.
\n\u2022 Paracetamol is relatively uniformly distributed throughout most body fluids. Plasma protein binding is variable; 20 to 30% may be bound at the concentrations encountered during acute intoxication.
\n\u2022 Paracetamol is metabolized in the liver and excreted in the urine mainly as the glucuronide and sulphate conjugates, with about 10% as glutathione conjugates. Less than 5% is excreted as unchanged paracetamol.<\/p>\n
Storage:
\n\u2022 Keep in a safe place, out of the reach and sight of children.
\n\u2022 Store at temperature not exceeding 25\u00b0 C, Protect from light.<\/p>\n","protected":false},"excerpt":{"rendered":"
Panadrex Pure Tablets contain 500 mg of paracetamol per tablet, offering analgesic and antipyretic effects. They are indicated for mild to moderate pain (e.g., headache, toothache, backache) and fever associated with colds, flu, or infections. Suitable for adults and children aged 10 years or older, following dosage guidelines.<\/p>\n","protected":false},"featured_media":192040,"template":"","meta":{"_uf_show_specific_survey":0,"_uf_disable_surveys":false},"product_cat":[21205],"product_tag":[21277],"class_list":["post-28995","product","type-product","status-publish","has-post-thumbnail","product_cat-analgesic-anti-inflammatory-antipyretic","product_tag-medication-used-as-pain-killer-and-in-case-of-fever-to-reduce-body-temperature-how-to-use-1-2-tab-every-8-hours-or-as-prescribed","first","instock","taxable","shipping-taxable","purchasable","product-type-simple"],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/targetphkw.com\/ar\/wp-json\/wp\/v2\/product\/28995","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/targetphkw.com\/ar\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/targetphkw.com\/ar\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/targetphkw.com\/ar\/wp-json\/wp\/v2\/media\/192040"}],"wp:attachment":[{"href":"https:\/\/targetphkw.com\/ar\/wp-json\/wp\/v2\/media?parent=28995"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/targetphkw.com\/ar\/wp-json\/wp\/v2\/product_cat?post=28995"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/targetphkw.com\/ar\/wp-json\/wp\/v2\/product_tag?post=28995"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}